The face of anti-ageing has changed forever. One Truth 818 Serum contains an active ingredient called TAM-818, the strongest of nearly 300,000 compounds tested over 11 years by award winning Telomere Biologist Dr. Bill Andrews and his team at Sierra Sciences. Clinical trials at Abich Labs in Italy show that after 30 days One Truth 818 decreased wrinkles by 14.04%, improved skin firmness by 20.33% and elasticity by 8.33%. Tried. Tested. The Truth is Out! How to use: Apply to face and neck morning and evening. Size: One Truth 818 contains 50ml of serum.